RESEARCH SERVICES

Preliminary Feasibility Assessment

            Literature review

            Patent search

            Product profile development

Preliminary Laboratory Feasibility Studies

            Analytical methods development for HPLC

            Formulation development

                        Solubility studies

                        Selection of excipients 

                                     and enhancers

                        In vitro flux studies

                               Human cadaver skin

                               Animal skin

                               Synthetic membranes

Optimization for preliminary product development

            Short term stability studies

            Extended formulation development to:

                      Enhance transdermal flux

                      Determine chemical stability

                      Optimize patch physical properties for:

                                    Cold flow

                                    Cohesion of laminates

                                    Skin adhesion

                                    Rheology

 

Management of Animal Studies (outside contractors)

            Systemic drug delivery

            Skin irritation and sensitization

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