Transdermal Research Pharm Lab

Long Island City (NY) and Paramus (NJ)

Research Services

TRPL provides one-stop research services for the development of transdermal/topical formulations

Preliminary Laboratory Feasibility Studies

  • Development and validation of analytical methods
  • Pre-formulation studies
  • Formulation Development
    • Expertise for 1-to-7-day transdermal drug delivery
    • Expertise for topical drug delivery
  • Solubility studies
  • Selection of excipients and enhancers
  • In vitro flux studies
    • Human cadaver skin
    • Animal skin
    • Synthetic membranes

Optimization for preliminary product development

  • Short term stability studies
  • Extended formulation development to
    • Optimize permeation
    • Determine chemical stability
  • Optimize physical properties of formulation
    • Cold flow
    • Cohesion of laminates
    • Skin adhesion
    • Rheology
    • Particle size distribution
    • Viscocity
    • Morphology
    • pH


  • 200+ Franz-diffusion cells
  • Semi-automated USP VII Dissolution apparatus
  • HPLC Systems (DAD equipped)
  • Differential Scanning Calorimeter
  • Rheometer
  • Texture Analyzer
  • Semi-automated Film Applicator
  • Ovens
  • Temperature control chambers
  • Laminator
  • Polarize Microscope
  • Freezer (-80C)

Management of Pre-clinical Studies (outside contractors)

  • Pharmacokinetic parameters
  • Skin irritation and sensitization


  • NYS DEA schedule I-IV license for research and manufacturing


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